Fmoc-Ala-Glu-Asn-Lys-NH2


CAS No. : 220701-06-4

220701-06-4
Price and Availability of CAS No. : 220701-06-4
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10mg $235 In-stock
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Cat. No. : HY-114174
M.Wt: 681.74
Formula: C33H43N7O9
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic;warming;heat to 80°C);H2O : ≥ 10 mg/mL
Introduction of 220701-06-4 :

Fmoc-Ala-Glu-Asn-Lys-NH2 is a selective asparagine endopeptidase (AEP) inhibitor peptide and suppresses amyloid precursor protein (APP) cleavage. AEP, a pH-controlled cysteine proteinase, is activated during ageing and mediates APP proteolytic processing[1]. In Vitro: Fmoc-Ala-Glu-Asn-Lys-NH2 antagonizes APP processing by AEP, whereas other small molecular inhibitors and inactive peptide AEQK were without effect[1].

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