WAY-151932
CAS No. : 220460-92-4
(Synonyms: VNA-932; WAY-VNA 932)
| Size | Price | Stock |
|---|---|---|
| 5mg | $93 | In-stock |
| 10mg | $150 | In-stock |
| 25mg | $300 | In-stock |
| 50mg | $480 | In-stock |
| 100mg | $768 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-19381 |
| M.Wt: | 402.88 |
| Formula: | C23H19ClN4O |
| Purity: | >98 % |
| Solubility: | DMSO : 200 mg/mL (ultrasonic) |
WAY-151932 is a vasopressin V2-receptor agonist with IC50 of 80.3 nM and 778 nM in human-V2 binding and V1a binding assay. IC50 & Target: IC50: 80.3 nM (human-V2 binding), 778 nM (human-V1a binding)[1] In Vitro: WAY-151932 (VNA-932) stimulates cAMP formation in LV2 cells expressing the hV2 receptors in a dose-dependent manner with an EC50 of 0.74±0.07 nM[2]. In Vivo: Oral administration of WAY-151932 (VNA-932) to water-loaded conscious rats produces a dose-dependent decrease in urine volume (ED50=0.14 mg/kg, 2.5% starch in water vehicle) and a corresponding increase in osmolality without altering the urine electrolyte excretion profile[2].
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