MY10
CAS No. : 2204270-73-3
| Size | Price | Stock |
|---|---|---|
| 5mg | $165 | In-stock |
| 10mg | $265 | In-stock |
| 25mg | $530 | In-stock |
| 50mg | $845 | In-stock |
| 100mg | $1350 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-123856 |
| M.Wt: | 384.36 |
| Formula: | C15H10F6OS2 |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic) |
MY10 is a potent and orally active receptor protein tyrosine phosphatase (RPTPβ/ζ) inhibitor. MY10 reduces NF-κB p65 expression. MY10 activates tyrosine phosphorylation of c-Met. MY10 prevents the alcohol-induced downregulation of Ptprz1 and Alk expression. MY10 attenuates binge-like ethanol consumption and ethanol reward. MY10 can be used in the study of neurological and vascular diseases[1][2][3][4][5].
IC50 & Target:receptor protein tyrosine phosphatase (RPTPβ/ζ)[1]
In Vitro:MY10 (0.1-10 μM, 24 h) decreases the viability of both SH-SY5Y neuroblastoma cells and BV2 microglial cells[2].
MY10 (10 μM) increases proliferation, migration, and tube formation of Ptprz1+/+ pulmonary microvascular endothelial cells (LMVECs)[4].
In Vivo:MY10 (100 mg/kg, p.o., 1 h before the voluntary alcohol consumption) reduces the alcohol consumption in rats[5].
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