Thioquinapiperifil
CAS No. : 220060-39-9
(Synonyms: KF31327 (free base))
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| Cat. No. : | HY-119611 |
| M.Wt: | 448.58 |
| Formula: | C24H28N6OS |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Thioquinapiperifil (KF31327 free base), a potent, selective and non-competitive phosphodiesterase-5 (PDE-5, IC50 of 0.074 nM) inhibitor, is used for sexual enhancement study[1][2].
IC50 & Target: IC50: 0.074 nM (PDE-5)[1].
In Vitro: Thioquinapiperifil can be found in dietary supplements[1].
Thioquinapiperifil (KF31327 free base) (0.1-10 μM) concentration dependently inhibits platelet aggregation. In the absence of nitroglycerin, higher concentrations 1 and 10 μM of Thioquinapiperifil (KF31327 free base) are required to inhibit platelet aggregation[2].
Thioquinapiperifil (KF31327 free base) and shows significant increase in cyclic GMP at 10 μM. After 5 min incubation, the mean cyclic GMP levels of Thioquinapiperifil (KF31327)-treated cells is 0.95±0.17 pmol/108 cells[2].
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