Isoescin IB


CAS No. : 219944-46-4

219944-46-4
Price and Availability of CAS No. : 219944-46-4
Size Price Stock
1mg $104 In-stock
5mg $260 In-stock
10mg $420 In-stock
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Cat. No. : HY-N0557
M.Wt: 1131.26
Formula: C55H86O24
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic)
Introduction of 219944-46-4 :

Isoescin IB is an isomer of Escin IB. Isoescin IB and Escin IB are the chief active ingredients in escin[1]. In Vitro: β-Escin (mainly consisting of escin Ia and escin Ib) is the major active ingredient in horse chestnut seeds extracts. β-escin can inhibit proliferation and/or induce apoptosis in various types of cancer cells including A549 cell, HT-29 cell, HCC cell, OVCAR3 cell and H-Ras 5RP7 cell. β-escin may be useful as a chemopreventive agent, especially for tumors associated with an inflammatory response[1].
As the minor component of escin, α-escin (mainly consisting of isoescin Ia and isoescin Ib) exhibits lower bioactivity[1].

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