9-[(3aR,4R,6R,6aR)-6-(aminomethyl)-2,2-dimethyl-tetrahydro-2H-furo[3,4-d][1,3]dioxol-4-yl]-9H-purin-6-amine


CAS No. : 21950-36-7

(Synonyms: 5'-Amino-5'-deoxy-2',3'-O-isopropylidineadenosine; 9-[(3aR,4R,6R,6aR)-6-(aminomethyl)-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-4-yl]purin-6-amine)

21950-36-7
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Cat. No. : HY-20593
M.Wt: 306.33
Formula: C13H18N6O3
Purity: >98 %
Solubility:
Introduction of 21950-36-7 :

Synthesis and evaluation of protein arginine N-methyltransferase inhibitors designed to simultaneously occupy both substrate binding sites By van Haren, Matthijs; van Ufford, Linda Quarles; Moret, Ed E.; Martin, Nathaniel I. From Organic & Biomolecular Chemistry (2015), 13(2), 549-560. Structure-Activity Relationship of Adenosine 5'-diphosphoribose at the Transient Receptor Potential Melastatin 2 (TRPM2) Channel: Rational Design of Antagonists By Moreau, Christelle; Kirchberger, Tanja; Swarbrick, Joanna M.; Bartlett, Stephen J.; Fliegert, Ralf; Yorgan, Timur; Bauche, Andreas; Harneit, Angelika; Guse, Andreas H.; Potter, Barry V. L. From Journal of Medicinal Chemistry (2013), 56(24), 10079-10102. Inhibitors of human histone methyltransferase EZH2, and methods of use thereof for treating cancer By Kuntz, Kevin Wayne; Knutson, Sarah Kathleen; Wigle, Timothy James Nelson From PCT Int. Appl. (2013), WO 2013138361 A1 20130919. Selective inhibitors of histone methyltransferase DOT1L By Song, Yongcheng; Chen, Pinhong; Diao, Jiasheng; Cheng, Gang; Deng, Lisheng; Anglin, Justin L.; Prasad, Venkataram B. V.; Yao, Yang From U.S. Pat. Appl. Publ. (2014), US 20140100184 A1 20140410.

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