SC-26196
CAS No. : 218136-59-5
| Size | Price | Stock |
|---|---|---|
| 5mg | $99 | In-stock |
| 10mg | $150 | In-stock |
| 25mg | $285 | In-stock |
| 50mg | $428 | In-stock |
| 100mg | $600 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-107410 |
| M.Wt: | 423.55 |
| Formula: | C27H29N5 |
| Purity: | >98 % |
| Solubility: | DMSO : 5 mg/mL (ultrasonic) |
SC-26196 is a potent, orally active Delta6 desaturase (D6D, FADS2) inhibitor (IC50=0.2 μM in a rat liver microsomal assay). Antiinflammatory properties[1]. IC50 & Target:IC50: 0.2 µM (Delta6 desaturase in a rat liver microsomal assay)[1] In Vitro:SC-26196 (200 nM) inhibits proliferation of peripheral blood mononuclear cells (PBMCs), but Not Jurkat Cells[2]. In Vivo:SC-26196 ( included in the diet at 0, 0.07, 0.21, or 0.7 mg/kg diet to achieve dosages of 0, 10, 30, and 100 mg/kg per day) causes a decrease in the calculated Δ6-desaturase index in both adipose tissue and liver. Feeding 100 mg SC-26196 per kg BW per day inhibits the Δ6-desaturase enzyme[3].
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