(±)-J-113397


CAS No. : 217461-40-0

217461-40-0
Price and Availability of CAS No. : 217461-40-0
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5mg $271 In-stock
10mg $434 In-stock
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50mg $1460 In-stock
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Cat. No. : HY-107721
M.Wt: 399.57
Formula: C24H37N3O2
Purity: >98 %
Solubility: DMSO : ≥ 300 mg/mL
Introduction of 217461-40-0 :

(±)-J-113397 is a potent and selective non-peptidyl ORL1 receptor antagonist with a Ki of 1.8 nM for cloned human ORL1. J-113397 inhibited nociceptin/orphanin FQ-stimulated GTPγS binding to CHO cells expressing ORL1 with an IC50 value of 5.3 nM. J-113397 can be used for researching the physiological roles of nociceptin/orphanin FQ[1]. IC50 & Target:Ki: 1.8 nM (human ORL1)[1]

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