UNC-2170 (maleate)
CAS No. : 2173992-60-2
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| Cat. No. : | HY-118897 |
| M.Wt: | 429.31 |
| Formula: | C18H25BrN2O5 |
| Purity: | >98 % |
| Solubility: |
UNC-2170 maleate is the maleate salt form of UNC-2170 (HY-115531). UNC-2170 maleate is a selective inhibitor for the methyl-lysine binding protein 53BP1, with IC50 of 29 µM and Kd of 22 µM. UNC-2170 maleate shows at least 17-fold selectivity for 53BP1 as compared to nine other methyl-lysine (Kme) reader proteins. 53BP1 is a Kme binding protein that plays a central role in DNA Damage Repair (DDR) pathways and is recruited to sites of double-strand breaks (DSB)[1].
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- UNC-2170 (maleate)
- Cat. No.:
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