BCX 1470 (methanesulfonate)
CAS No. : 217099-44-0
| Size | Price | Stock |
|---|---|---|
| 5mg | $312 | In-stock |
| 10mg | $500 | In-stock |
| 25mg | $1000 | In-stock |
| 50mg | $1500 | In-stock |
| 100mg | $2250 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-50875 |
| M.Wt: | 398.48 |
| Formula: | C15H14N2O5S3 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 33.33 mg/mL |
BCX 1470 methanesulfonate inhibits the esterolytic activity of factor D (IC50=96 nM) and C1s (IC50=1.6 nM), 3.4- and 200-fold better, respectively, than that of trypsin. IC50 & Target: IC50: 96 nM (Factor D); 1.6 nM (C1s); 326 nM (Trypsin) In Vitro: BCX 1470 methanesulfonate is serine protease inhibitor. BCX 1470 methanesulfonate blocks the esterolytic and hemolytic activities of the complement enzymes Cls and factor D in vitro, also blocked development of RPA-induced edema in the rat.
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