BCX 1470


CAS No. : 217099-43-9

217099-43-9
Price and Availability of CAS No. : 217099-43-9
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Cat. No. : HY-50874
M.Wt: 302.37
Formula: C14H10N2O2S2
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 217099-43-9 :

BCX 1470 inhibits the esterolytic activity of factor D (IC50=96 nM) and C1s (IC50=1.6 nM), 3.4- and 200-fold better, respectively, than that of trypsin. IC50 & Target: IC50: 96 nM (Factor D); 1.6 nM (C1s); 326 nM (Trypsin) In Vitro: BCX 1470 is serine protease inhibitor. BCX 1470 blocks the esterolytic and hemolytic activities of the complement enzymes Cls and factor D in vitro, also blocked development of RPA-induced edema in the rat.

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