dBRD9
CAS No. : 2170679-45-3
| Size | Price | Stock |
|---|---|---|
| 5mg | $400 | In-stock |
| 10mg | $640 | In-stock |
| 25mg | $1280 | In-stock |
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| 100 mg | Get quote | |
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| Cat. No. : | HY-117690 |
| M.Wt: | 783.83 |
| Formula: | C40H45N7O10 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
dBRD9,a PROTAC, can selective degrades BRD9. dBRD9 improves the bromine domain binding profile and reduces the binding activity of the whole BET family[1].
In Vitro: dBRD9 (0.5-5000 nM; 4 h) reduces the expression of BRD9 with concentration-dependent manner, but has insignificant effect on the expression of actin, BRD4 and BRD7 in MOLM-13 cells[1].
dBRD9 (100 nM; 2 h) is selective for BRD9 in MOLM-13 cells[1].
dBRD9 (7 d) has anti-proliferation effect on EOL-1 and MOML-13 cell lines[1].
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