AR-C117977


CAS No. : 216685-07-3

216685-07-3
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Cat. No. : HY-114602
M.Wt: 468.63
Formula: C25H28N2O3S2
Purity: >98 %
Solubility:
Introduction of 216685-07-3 :

AR-C117977 is a potent monocarboxylate transporter (MCT1) inhibitor. AR-C117977 prolongs the survival of skin and heart sllograft. AR-C117977 inhibits the development of transplant arteriosclerosis in aortic allografts partially, but was unable to inhibit alloantibody production after transplantation. AR-C117977 shows potent immunosuppressive properties in vivo effectively preventing acute but not chronic allograft rejection in the mouse[1].

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