Quercetin 3-O-β-D-glucofuranoside

Quercetin 3-O-β-D-glucofuranoside is an effective antioxidant and an eosinophilic inflammation suppressor. In Vitro:Quercetin 3-O-β-D-glucofuranoside occurs widely in plants. 10 μM of Quercetin 3-O-β-D-glucofuranoside partially but significantly blunt the negative effect of H₂O₂ on RGC-5 cells, as the viability of cells in the presence of H₂O₂ is increased from approximately 63% to 83% and 90% at 10 and 50 μM, respectively. Indeed, 50 μM Quercetin 3-O-β-D-glucofuranoside is more effective as a neuroprotectant than the same concentration of EGCG^[1]. In Vivo:In animals receiving Quercetin 3-O-β-D-glucofuranoside, eosinophil counts are lower in the BALF, blood and lung parenchyma. Neutrophil counts in blood and IL-5 levels in lung homogenate are lower only in Isoquercitrin-treated mice. No alterations in mononuclear cell numbers were observed^[2].