BAY-218
CAS No. : 2162982-11-6
(Synonyms: AHR antagonist 1)
| Size | Price | Stock |
|---|---|---|
| 5mg | $110 | In-stock |
| 10mg | $165 | In-stock |
| 25mg | $319 | In-stock |
| 50mg | $510 | In-stock |
| 100mg | $795 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-111449 |
| M.Wt: | 401.82 |
| Formula: | C20H17ClFN3O3 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 250 mg/mL |
BAY-218 (AHR antagonist 1) is an aryl hydrocarbon receptor (AHR) antagonist. BAY-218 has AHR inhibitory activity with an IC50 of 39.9 nM in in U87 glioblastoma cells. BAY-218 can be used for the research of cancer or conditions with dysregulated immune responses[1].
IC50 & Target:IC50: 39.9 nM (AHR in human cell line)[1]
In Vitro:BAY-218 (example 23) (72 pM-20 μM) has AHR inhibitory activity with an IC50 of 39.9 nM in in U87 glioblastoma cells[1].
BAY-218 (1 nM-3 μM) has CYP1A1 inhibitory activity with an IC50 of 70.7 nM in human monocytic U937 cell line[1].
BAY-218 (1 μM) reverses KA-induced inhibition of TNFα production by LPS stimulated human monocytes[1].
In Vivo:BAY-218 (example 23) (p.o; 30 mg/kg; bid) has good anti-tumor effect combinated with aPD-L1[1].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- BAY-218
- Cat. No.:
- HY-111449
- Quantity:
Your information is safe with us.