α5IA
CAS No. : 215874-86-5
(Synonyms: L-822179)
| Size | Price | Stock |
|---|---|---|
| 5mg | $84 | In-stock |
| 10mg | $132 | In-stock |
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| 100 mg | Get quote | |
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| Cat. No. : | HY-116622 |
| M.Wt: | 362.35 |
| Formula: | C17H14N8O2 |
| Purity: | >98 % |
| Solubility: | DMSO : 1.25 mg/mL (ultrasonic;warming;heat to 60°C) |
α5IA (L-822179) is a selective α5 GABAA receptor inverse agonist with neuroprotective potential[1].
In Vitro:α5IA (100 nM, 5 days) can significantly reduce Aβ 1-42-induced cell death in primary mouse hippocampal cultures[1].
In Vivo:α5IA (5 mg/kg, i.p., once) can sustain restoration of spatial learning ability in Ts65Dn mice, and long-term recognition of spatial memory deficits[2].
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