KRAS G12C inhibitor 5
CAS No. : 2158297-63-1
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| Cat. No. : | HY-114168 |
| M.Wt: | 551.68 |
| Formula: | C32H37N7O2 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
KRAS G12C inhibitor 5 is a KRas G12C inhibitor extracted from patent WO2017201161A1, Compound example 147[1]. IC50 & Target: KRas G12C[1] In Vitro: Kirsten Rat Sarcoma 2 Viral Oncogene Homolog (KRas) is a small GTPase and a member of the Ras family of oncogenes. KRas serves a molecular switch cycling between inactive (GDP -bound) and active (GTP -bound) states to transduce upstream cellular signals received from multiple tyrosine kinases to downstream effectors to regulate a wide variety of processes, including cellular proliferation[1].
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