Betamethasone valerate
CAS No. : 2152-44-5
(Synonyms: Betamethasone 17-valerate)
| Size | Price | Stock |
|---|---|---|
| 25mg | $55 | In-stock |
| 50mg | $88 | In-stock |
| 100mg | $132 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-B0727 |
| M.Wt: | 476.58 |
| Formula: | C27H37FO6 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
Betamethasone valerate (Betamethasone 17-valerate), the 17-valerate ester of Betamethasone, is a topical corticosteroid with anti-inflammatory activity. Betamethasone valerate is used in the treatment of recurrent aphthous stomatitis. Betamethasone valerate inhibits the binding of the radiolabeled glucocorticoid dexamethasone (3H dexamethasone) to human epidermis and mouse skin with IC50s of 5 and 6 nM, respectively[1][2][3].
In Vivo: Betamethasone valerate (10 mg; 5 minutes; applied to the irritated site with a micro spatula) ointment inhibits about 50% of the ear edema without thymus atrophy[4].
Betamethasone-17-valerate ointment (50 mg) inhibits homologous passive cutaneous anaphylaxis[4].
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