Lofexidine (hydrochloride) (Standard)
CAS No. : 21498-08-8
(Synonyms: Baq-168 (Standard); MDL-14042 (Standard))
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| Cat. No. : | HY-B1052R |
| M.Wt: | 295.59 |
| Formula: | C11H13Cl3N2O |
| Purity: | >98 % |
| Solubility: |
Lofexidine (Baq-168) hydrochloride Standard is the analytical standard of Lofexidine hydrochloride (HY-B1052). This product is intended for research and analytical applications. Lofexidine hydrochloride (Baq-168) is an orally active agonist of the imidazoline I1 receptor (imidazoline I1 receptor) (Ki: 1.9 nM) and α2-adrenergic receptor (α2-adrenergic receptor). Lofexidine hydrochloride binds to the α2A-adrenergic receptor, reduces sympathetic outflow, lowers blood pressure, and exhibits vasoconstrictive effects. Lofexidine hydrochloride regulates the expression of c-fos and alleviates opioid withdrawal symptoms. Lofexidine hydrochloride is applicable to research on opioid addiction and withdrawal[1][2].
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