BPK-29
CAS No. : 2143467-62-1
| Size | Price | Stock |
|---|---|---|
| 5mg | $330 | In-stock |
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| 50 mg | Get quote | |
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| Cat. No. : | HY-122054 |
| M.Wt: | 470.00 |
| Formula: | C26H32ClN3O3 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
BPK-29 is a specific ligand that disrupts the atypical orphan nuclear receptor NR0B1-protein (such RBM45 and SNW1) interactions by covalently modifying C274. BPK-29 impairs the anchorage-independent growth of KEAP1-mutant cancer cells[1]. In Vitro: BPK-29 substantially engages NR0B1 with good overall proteomic selectivity in KEAP1-mutant Non-Small Cell Lung Cancers[1].
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