Razoxane
CAS No. : 21416-67-1
(Synonyms: ICRF 159)
| Size | Price | Stock |
|---|---|---|
| 100mg | $86 | In-stock |
| 250mg | $129 | In-stock |
| 1g | $323 | In-stock |
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| 10 g | Get quote | |
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| Cat. No. : | HY-119425 |
| M.Wt: | 268.27 |
| Formula: | C11H16N4O4 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Razoxane (ICRF 159), a EDTA (HY-Y0682) derivative, is an orally active antiangiogenic topoisomerase II inhibitor. Razoxane has antineoplastic, antiangiogenic, and antimetastatic activities. Razoxanecan be used for the research of renal cell carcinoma (RCC), lung cancer and melanoma cancer[1][2].
In Vivo:Razoxane (30 mg/kg; i.p.) exhibits antimetastatic effects in a rat osteosarcoma model[2].
Early treatment with Razoxane (30 mg/kg i.p. from day -2 to +14) shows a greater inhibition of pulmonary metastases than later treatment (30 mg/kg i.p. from day +14 to +28 after transplantation)[2].
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