N2-Methylguanosine
CAS No. : 2140-77-4
| Size | Price | Stock |
|---|---|---|
| 5mg | $156 | In-stock |
| 10mg | $250 | In-stock |
| 25mg | $350 | In-stock |
| 50mg | $500 | In-stock |
| 100mg | $700 | In-stock |
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| Cat. No. : | HY-111647 |
| M.Wt: | 297.27 |
| Formula: | C11H15N5O5 |
| Purity: | >98 % |
| Solubility: | H2O : 1 mg/mL (ultrasonic;warming;heat to 80°C);DMSO : 7.69 mg/mL (ultrasonic) |
N2-Methylguanosine is a commonly modified nucleoside in rRNA and tRNA, with specific distributions in both E. coli rRNA and eukaryotic tRNA. N2-Methylguanosine can be found in urine. N2-Methylguanosine affects the structure and stability of RNA[1][2][3].
In Vitro:N2-Methylguanosine can form a stable complex with C, and changes in its conformation and stacking may play a crucial role in the process of tRNA recognizing synthetases[1].
N2-Methylguanosine can alter the base-pairing behavior of RNA and affect the stability of RNA duplexes and hairpin structures. Its mechanism of action is related to steric hindrance, changes in hydrogen bonds, and alterations in the hydration pattern[3].
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