1-Methylinosine


CAS No. : 2140-73-0

(Synonyms: N1-Methylinosine)

2140-73-0
Price and Availability of CAS No. : 2140-73-0
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Cat. No. : HY-113139
M.Wt: 282.25
Formula: C11H14N4O5
Purity: >98 %
Solubility: DMSO : 83.33 mg/mL (ultrasonic)
Introduction of 2140-73-0 :

1-Methylinosine (N1-MetHYlinosine) is a modified nucleotide located at position 37 of eukaryotic tRNA, 3' to the tRNA anticodon. 1-Methylinosine is a minor metabolite of 1-methyladenosine (HY-113081). The level of 1-Methylinosine is significantly elevated in urine samples from breast cancer models[1][2]. In Vivo:1-Methylinosine is a minor endogenous metabolite of 1-methyladenosine in male Sprague-Dawley rats, accounting for approximately 2.6% of the total excreted radioactivity following intravenous administration of 1-methyladenosine[2].

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