5,7-Dimethoxyflavone
CAS No. : 21392-57-4
| Size | Price | Stock |
|---|---|---|
| 5mg | $30 | In-stock |
| 10mg | $45 | In-stock |
| 25mg | $90 | In-stock |
| 50mg | $135 | In-stock |
| 100mg | $216 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-N5011 |
| M.Wt: | 282.29 |
| Formula: | C17H14O4 |
| Purity: | >98 % |
| Solubility: | DMSO : 62.5 mg/mL (ultrasonic;warming;heat to 60°C) |
5,7-Dimethoxyflavone is one of the major components of Kaempferia parviflora, has anti-obesity, anti-inflammatory, and antineoplastic effects. 5,7-Dimethoxyflavone inhibits cytochrome P450 (CYP) 3As. 5,7-Dimethoxyflavone is also a potent Breast Cancer Resistance Protein (BCRP) inhibitor[1][2].
IC50 & Target:P450 (CYP) 3As[1];
Breast Cancer Resistance Protein (BCRP)[2]
In Vitro:5,7-Dimethoxyflavone (5 and 50 μM, 1 h) inhibits Bcrp1-mediated Sorafenib efflux in MDCK/Bcrp1 cells[2].
5,7-Dimethoxyflavone (0-25 μM, 48 h ) induces melanogenesis by increasing cAMP in B16F10 melanoma cells[4].
5,7-Dimethoxyflavone (0-20 μM, 8 days) inhibits lipid accumulation by reducing TG accumulation in 3T3-L1 adipocytes, and inhibits adipocyte differentiation[5].
5,7-Dimethoxyflavone (0-100 μM, 48 h) inhibits proliferation, induces oxidative stress and induces apoptosis in VK2/E6E7 and End1/E6E7 cells[6].
In Vivo:5,7-Dimethoxyflavone (10 mg/kg, p.o., once a day for 10 days) reduces liver CYP3A11 and CYP3A25 protein expression levels in mice[1].
5,7-Dimethoxyflavone (25 and 50 mg/kg, p.o.) inhibits sarcopenia in aged mice[3].
5,7-Dimethoxyflavone (50 mg/kg/day, p.o., for 6 weeks) decreases body weight gain and inhibits fatty liver in HFD mice[5].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- 5,7-Dimethoxyflavone
- Cat. No.:
- HY-N5011
- Quantity:
Your information is safe with us.