6-Hydroxy-DOPA


CAS No. : 21373-30-8

21373-30-8
Price and Availability of CAS No. : 21373-30-8
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5mg $130 In-stock
10mg $208 In-stock
25mg $416 In-stock
50mg $665 In-stock
100mg $998 In-stock
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Cat. No. : HY-110286
M.Wt: 213.19
Formula: C9H11NO5
Purity: >98 %
Solubility: DMSO : 50 mg/mL (ultrasonic)
Introduction of 21373-30-8 :

6-Hydroxy-DOPA is a selective and effective allosteric inhibitor of the RAD52 ssDNA binding domain. 6-Hydroxy-DOPA can be used for the research of cancer[1]. IC50 & Target: RAD52[1] In Vitro: 6-Hydroxy-DOPA (0~20 μM; U20S cells) selectively inhibits RAD52-mediated recombination. 6-Hydroxy-DOPA (0~10 μM; HEK293T cells) decreases the number of eGFP-RAD52 foci in a dose-dependent manner. 6-Hydroxy-DOPA (5~75 μM; HCC1937 cells) selectively reduces the viability of the BRCA1-deficient triple-negative breast cancer cell line HCC1937[1].

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