Foliglurax (monohydrochloride)


CAS No. : 2133294-96-7

(Synonyms: PXT002331 (monohydrochloride))

2133294-96-7
Price and Availability of CAS No. : 2133294-96-7
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Cat. No. : HY-108703A
M.Wt: 457.97
Formula: C23H24ClN3O3S
Purity: >98 %
Solubility: DMSO : 5 mg/mL (ultrasonic);H2O : 25 mg/mL (ultrasonic)
Introduction of 2133294-96-7 :

Foliglurax monohydrochloride (PXT002331 monohydrochloride) is a highly selective and potent, brain-penetrant metabotropic glutamate receptor 4 positive allosteric modulator (mGluR4 PAM) , with an EC50 of 79 nM[1]. Antiparkinsonian effect[1]. In Vitro: Foliglurax, a highly selective and potent mGlu4 receptor PAM with a marked brain-penetrance feature, might revolutionize the field of mGlu4 receptor drug targeting in CNS disorders[2].

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