SW-100
CAS No. : 2126744-35-0
| Size | Price | Stock |
|---|---|---|
| 5mg | $140 | In-stock |
| 10mg | $225 | In-stock |
| 50mg | $560 | In-stock |
| 100mg | $840 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-115475 |
| M.Wt: | 316.78 |
| Formula: | C17H17ClN2O2 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 125 mg/mL |
SW-100, a selective histone deacetylase 6 (HDAC6) inhibitor with an IC50 of 2.3 nM, shows at least 1000-fold selectivity for HDAC6 relative to all other HDAC isozymes. SW-100 displays a significantly improved ability to cross the blood-brain-barrier[1]. IC50 & Target: IC50: 2.3 nM (Histone deacetylase 6)[1] In Vitro: SW-100 (0.01-10 µM; 48 hours) shows obvious increase in the acetylated α-tubulin levels in a dose-dependent manner[1]. In Vivo: SW-100 (20 mg/kg; i.p.; twice a day for two days) ameliorates several memory and learning impairments including novel object recognition, temporal ordering, and coordinate and categorical spatial processing in mouse model of Fragile X syndrome[1].
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