Gp100 (25-33), human
CAS No. : 212370-40-6
(Synonyms: Hgp100 (25-33))
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| Cat. No. : | HY-P1585 |
| M.Wt: | 1155.31 |
| Formula: | C52H82N16O14 |
| Purity: | >98 % |
| Solubility: | H2O : 37.5 mg/mL (ultrasonic;warming) |
Gp100 (25-33), human (Hgp100 (25-33)) is the amino acids 25-33 fragment of the human melanoma antigen. Gp100 (25-33), human is a 9-amino acid (AA) epitope restricted by MHC class I H-2Db and recognized by the T cells. Gp100 (25-33), human has immunogenicity and induces specific T cells. Gp100 (25-33), human can be used for the cancer research, such as melanoma[1].
In Vitro:Gp100 (25-33), human (recombinant vaccinia virus (rVV) encoding human gp100) (24 h) generates CD4-CD8+ lytic T lymphocyte in splenocytes[1].
In Vivo:Gp100 (25-33), human (T cells induced by rVVgp100) (i.p., twice a day for 5 days) shows anti-tumor effect in B16 tumor mice models[1].
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