Ungeremine
CAS No. : 2121-12-2
(Synonyms: Lycobetaine; Oxylycorine (free base))
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| Cat. No. : | HY-N1971 |
| M.Wt: | 266.27 |
| Formula: | C16H12NO3+ |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Ungeremine, a phenanthridine type alkaloid, is extracted of the bulbs of Pancratium Illyricum. Ungeremine effectively targets mammalian as well as bacterial type I and type II topoisomerases. Ungeremine displays cytotoxic activity towards the 9 cancer cell lines, including drug-sensitive and MDR phenotypes. Ungeremine induced ferroptosis, necroptosis, autophagy as well as apoptosis mediated by caspase activation, MMP alteration and increase ROS production[1][2].
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