Indolmycin
CAS No. : 21200-24-8
(Synonyms: TAK-083; PA-155A)
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| Cat. No. : | HY-117319 |
| M.Wt: | 257.29 |
| Formula: | C14H15N3O2 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Indolmycin (TAK-083), an antibiotic, is a competitive inhibitor of prokaryotic tryptophanyl-tRNA synthetase (TrpS). Indolmycin (TAK-083) possesses both anti-viral and anti-bacterial activity[1][2][3]. In Vitro: Indolmycin was bacteriostatic and demonstrated good activity against MSSA (methicillinsusceptible Staphylococcus aureus), MRSA (methicillin-resistant S. aureus) and VISA (vancomycinintermediate S. aureus), including strains resistant to mupirocin or fusidic acid. Indolmycin MICs for 20 strains ranged from 8 to 32 mg/L, whereas a single strain exhibited high-level resistance (MIC 128 mg/L)[2].
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