R18


CAS No. : 211364-78-2

(Synonyms: PHCVPRDLSWLDLEANMCLP)

211364-78-2
Price and Availability of CAS No. : 211364-78-2
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Cat. No. : HY-P1039
M.Wt: 2309.69
Formula: C101H157N27O29S3
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 211364-78-2 :

R18 is a peptide antagonists of 14-3-3, with a KD of 70-90 nM. R18 efficiently blocks the binding of 14-3-3 to the kinase Raf-1, a physiological ligand of 14-3-3, and effectively abolished the protective role of 14-3-3 against phosphatase-induced inactivation of Raf-1[1].

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