STAT5-IN-2
CAS No. : 2111834-61-6
| Size | Price | Stock |
|---|---|---|
| 5mg | $400 | In-stock |
| 10mg | $680 | In-stock |
| 25mg | $1180 | In-stock |
| 50mg | $1770 | In-stock |
| 100mg | $2650 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-102048 |
| M.Wt: | 397.51 |
| Formula: | C26H27N3O |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
STAT5-IN-2 is a STAT5 inhibitor, extracted from reference 1, example 17f. STAT5-IN-2 has potent antileukemic effect[1].
IC50 & Target: EC50: 9 μM (K562 cells), 5 μM (KU812 cells)[1]
In Vitro: STAT5-IN-2 has EC50 values of 9 μM and 5 μM in K562 and KU812 cells, respectively[1].
STAT5-IN-2 (100 nM-50 µM; 48 hours) has EC50 values of 2.6 µM and 3.5 µM in KG1a and MV-4-11 cells, respectively[1].
STAT5-IN-2 (10 µM; 48 hours) induces apoptosis in all cell lines (K562, KU812, KG1a and MV-4-11 cells)[1].
STAT5-IN-2 (10 µM; 24 hours) blocks phosphorylation of STAT5[1].
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