BMY 7378 (free base)
CAS No. : 21102-94-3
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| Cat. No. : | HY-116982 |
| M.Wt: | 385.50 |
| Formula: | C22H31N3O3 |
| Purity: | >98 % |
| Solubility: |
BMY 7378 (free base) is a selective antagonist of α1D-adrenoceptor (α1D-AR). BMY 7378 (free base) binds to membranes expressing the cloned rat α1D-AR with a >100-fold higher affinity (Ki=2 nM) than binding to either the cloned rat α1A-AR (Ki=800 nM) or the hamster α1B-AR (Ki=600 nM). BMY 7378 (free base) is a 5-HT1A receptor partial agonist[1][2].
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