Z-YVAD-FMK


CAS No. : 210344-97-1

210344-97-1
Price and Availability of CAS No. : 210344-97-1
Size Price Stock
1mg $220 In-stock
5mg $500 In-stock
10mg $750 In-stock
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100 mg Get quote
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Cat. No. : HY-P1009
M.Wt: 630.66
Formula: C31H39FN4O9
Purity: >98 %
Solubility: DMSO : 125 mg/mL (ultrasonic)
Introduction of 210344-97-1 :

Z-YVAD-FMK is a?cell-permeable?caspase-1 and -4 inhibitor with?anti-inflammatory and anti-tumor activities[1]. In Vitro: Z-YVAD-FMK (100 μM; 24 hours) significantly downregulated the growth inhibition induced by butyrate in Caco-2 cells[1].
Z-YVAD-FMK (20 μM; pre 1 hour; 24 hours) attenuates the apoptotic induction of III-10 on both HepG2 and BEL-7402 cells, the apoptotic rate of -10 on HepG2 cells is reduced by Z-VAD-FMK from 19.88% to 8.34%, while that on BEL-7402 cells is reduced from 17.56% to 11.98%[4].

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