Z-VEID-FMK
CAS No. : 210344-96-0
(Synonyms: Z-VE(OMe)ID(OMe)-FMK)
| Size | Price | Stock |
|---|---|---|
| 5mg | $360 | In-stock |
| 10mg | $600 | In-stock |
| 25mg | $960 | In-stock |
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| 100 mg | Get quote | |
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| Cat. No. : | HY-P1007 |
| M.Wt: | 652.71 |
| Formula: | C31H45FN4O10 |
| Purity: | >98 % |
| Solubility: | DMSO : 250 mg/mL (ultrasonic) |
Z-VEID-FMK (Z-VE(OMe)ID(OMe)-FMK) is a selective and irreversible caspase-6 peptide inhibitor. Z-VEID-FMK alleviates the drug-induced augmentation of caspase-6 activity, DNA fragmentation, and cell apoptosis[1][2]. In Vitro:Z-VEID-FMK (Z-VE(OMe)ID(OMe)-FMK; pretreated 50 μM; for 1 h) decreases drug (200 μM; for another 16 h)-induced caspase-6 activity by 53% and apoptotic by 58%, alleviated S-(+)-ketamine-caused DNA fragmentation by 44% in HepG2 cells[1].
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