| Size | Price | Stock |
|---|---|---|
| 100 mg | Get quote | |
| 250 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
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Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-103630 |
| M.Wt: | 915.77 |
| Formula: | C44H44Cl2N8O10 |
| Purity: | >98 % |
| Solubility: |
PROTAC Her3 Degrader-2 is a Her3 PROTAC degrader with an IC50 < 10 nM. PROTAC Her3 Degrader-2 recruits Her3 to E3 ubiquitin ligase to achieve selective degradation. PROTAC Her3 Degrader-2 can be used in the research of breast cancer, lung cancer, head and neck cancer, and prostate cancer[1].
In Vitro:PROTAC Her3 Degrader-2 (Compound CY2) exhibits extremely potent target kinase binding activity in vitro, with an IC50 < 10 nM[1].
PROTAC Her3 Degrader-2 exhibits no significant Her3 protein degradation in PC9-GR4 or Ovacar 8 cell lines[1].
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