GPR40 agonist 4
CAS No. : 2102196-57-4
| Size | Price | Stock |
|---|---|---|
| 5mg | $120 | In-stock |
| 10mg | $180 | In-stock |
| 25mg | $350 | In-stock |
| 50mg | $550 | In-stock |
| 100mg | $750 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-103083 |
| M.Wt: | 416.87 |
| Formula: | C21H17ClO5S |
| Purity: | >98 % |
| Solubility: | DMSO : 160 mg/mL (ultrasonic;warming) |
GPR40 agonist 4 is a potent free fatty acid receptor 1 (FFA1/ GPR40) agonist with a pEC50 of 7.54. IC50 & Target: pEC50: 7.54 (FFA1/GPR40)[1] In Vitro: GPR40 agonist 4 tends to have a low risk of activating caspase-3/7[1]. In Vivo: Single oral administration of GPR40 agonist 4 (compound 20) robustly reduces the plasma glucose excursion and enhances insulin secretion during an oral glucose tolerance test (OGTT) in a dose-dependent manner from 1 to 10 mg/kg when GPR40 agonist 4 is dosed 60 min prior to the oral glucose challenge. The area under the curve of blood glucose (AUC0-120min) and blood insulin (AUC0-120min) reveal that the minimum effective dose of GPR40 agonist 4 is 3 mg/kg. The hyperglycemia state is also markedly improved in GPR40 agonist 4 (20 mg/kg) treated group[1].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- GPR40 agonist 4
- Cat. No.:
- HY-103083
- Quantity:
Your information is safe with us.