Gboxin
CAS No. : 2101315-36-8
| Size | Price | Stock |
|---|---|---|
| 5mg | $105 | In-stock |
| 10mg | $165 | In-stock |
| 25mg | $330 | In-stock |
| 50mg | $520 | In-stock |
| 100mg | $820 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-111651 |
| M.Wt: | 392.96 |
| Formula: | C22H33ClN2O2 |
| Purity: | >98 % |
| Solubility: | DMSO : 32.5 mg/mL (ultrasonic);H2O : 10 mg/mL (ultrasonic) |
Gboxin is an oxidative phosphorylation (OXPHOS) inhibitor that targets glioblastoma. Gboxin inhibits the activity of F0F1 ATP synthase. Antitumour activity[1]. IC50 & Target: F0F1 ATP synthase[1] In Vitro: Gboxin (0-15 μM; 96 hours) specifically inhibit the growth of primary ‘high-throughput GBM sphere’ (HTS) cells but not that of cycling primary low-passage mouse embryonic fibroblasts (MEFs) or astrocytes[1].
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