PROTAC BRD4-binding moiety 1
CAS No. : 2101200-10-4
| Size | Price | Stock |
|---|---|---|
| 5mg | $410 | In-stock |
| 10mg | $657 | In-stock |
| 25mg | $1315 | In-stock |
| 50mg | $2200 | In-stock |
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| Cat. No. : | HY-107442 |
| M.Wt: | 371.43 |
| Formula: | C23H21N3O2 |
| Purity: | >98 % |
| Solubility: | DMSO : 120 mg/mL (ultrasonic) |
PROTAC BRD4-binding moiety 1 is a ligand for BRD4. PROTAC BRD4-binding moiety 1 binds to cereblon ligand via a linker to form PROTAC to degrade BRD4 (HY-133136)[1]. PROTAC BRD4-binding moiety 1 is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. In Vitro: PROTAC BRD4 Degrader-2 is an efficacious PROTAC BRD4 degrader with an IC50 of 14.2 nM against BRD4 BD1[1].
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- PROTAC BRD4-binding moiety 1
- Cat. No.:
- HY-107442
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