Compound E (GMP)
CAS No. : 209986-17-4
(Synonyms: γ-Secretase-IN-1 (GMP))
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| Cat. No. : | HY-14176G |
| M.Wt: | 490.50 |
| Formula: | C27H24F2N4O3 |
| Purity: | >98 % |
| Solubility: |
Compound E (GMP) is a GMP-grade Compound E (HY-14176). GMP-grade small molecules can be used as adjuvant reagents in cell therapy. Compound E is a γ-secretase inhibitor. Compound E inhibits β-amyloid(40), β-amyloid(42), and Notch γ-secretase cleavage with IC50 values of 0.24, 0.37, and 0.32 nM, respectively[1][2].
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