SMS2-IN-1
CAS No. : 2098890-15-2
| Size | Price | Stock |
|---|---|---|
| 1mg | $214 | In-stock |
| 5mg | $450 | In-stock |
| 10mg | $800 | In-stock |
| 25mg | $1650 | In-stock |
| 50mg | $2550 | In-stock |
| 100mg | $3800 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-102041 |
| M.Wt: | 681.67 |
| Formula: | C34H37F6N3O5 |
| Purity: | >98 % |
| Solubility: | DMSO : 27.78 mg/mL (ultrasonic) |
SMS2-IN-1 is a potent and highly selective sphingomyelin synthase 2 (SMS2) inhibitor with an IC50 of 6.5 nM and a Kd of 37 nM. SMS2-IN-1 shows 150-fold selectivity for SMS2 over SMS1 (IC50 of 1000 nM)[1].
IC50 & Target: IC50: 6.5 nM (SMS2), 1000 nM (SMS1)[1]
Kd: 37 nM (SMS2)[1]
In Vitro: AS/MS binding experiments are conducted using these SMS2-mutant membrane fractions, SMS2-IN-1 (compound 2) binds to the S217A, H272A, and D276A mutants. S227 and H229 are pivotal amino acid residues for the binding of SMS2-IN-1 to SMS2[1].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- SMS2-IN-1
- Cat. No.:
- HY-102041
- Quantity:
Your information is safe with us.