(S,R,S)-AHPC-PEG2-NH2 (hydrochloride)


CAS No. : 2097973-72-1

(Synonyms: VH032-PEG2-NH2 (hydrochloride); VHL Ligand-Linker Conjugates 3 (hydrochloride); E3 ligase Ligand-Linker Conjugates 6)

2097973-72-1
Price and Availability of CAS No. : 2097973-72-1
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10mg $45 In-stock
25mg $65 In-stock
50mg $112 In-stock
100mg $157 In-stock
250mg $276 In-stock
500mg $551 In-stock
1g $770 In-stock
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Cat. No. : HY-103603
M.Wt: 612.18
Formula: C28H42ClN5O6S
Purity: >98 %
Solubility: H2O : 100 mg/mL (ultrasonic);DMSO : 150 mg/mL (ultrasonic)
Introduction of 2097973-72-1 :

(S,R,S)-AHPC-PEG2-NH2 hydrochloride (VH032-PEG2-NH2 hydrochloride) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker used in the synthesis of PROTACs[1]. IC50 & Target: E3 Ligase Ligand-Linker Conjugate[1] In Vitro: PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

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