Stafib-2
CAS No. : 2097938-74-2
| Size | Price | Stock |
|---|---|---|
| 1mg | $264 | In-stock |
| 5mg | $660 | In-stock |
| 10mg | $940 | In-stock |
| 25mg | $1390 | In-stock |
| 50mg | $1880 | In-stock |
| 100mg | $2560 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-112648 |
| M.Wt: | 644.46 |
| Formula: | C28H26N2O12P2 |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic) |
Stafib-2 is a potent and selctive inhibitor of the transcription factor STAT5b, with an IC50 of 82 nM and 1.7 μM for STAT5b and STAT5a, respectively. Stafib-2 exhibits poor cell permeability[1].
IC50 & Target: IC50: 82 nM (STAT5b)[1]
In Vitro: Stafib-2 has an extremely high affinity for STAT5b (Ki=8.8 nM)[1].
Stafib-2 (3-10 μM; 4-48 h) does not show significant activity in K562 and MDA-MB-231 cells[1].
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