FASN-IN-3
CAS No. : 2097262-60-5
| Size | Price | Stock |
|---|---|---|
| 5mg | $120 | In-stock |
| 10mg | $195 | In-stock |
| 25mg | $330 | In-stock |
| 50mg | $460 | In-stock |
| 100mg | $640 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-U00436 |
| M.Wt: | 384.47 |
| Formula: | C24H24N4O |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
FASN-IN-3 is a fatty acid synthase (FASN) inhibitor extracted from patent US20170119786A1, compound 242A[1]. IC50 & Target:FASN[1] In Vitro: Human PBMC and monocytes in cell cultures are stimulated with lipopolysaccharide (LPS), a Toll 4 receptor agonist, or lipoteichoic acid (LTA), a Toll 2 receptor agonist. Stimulation with either LPS or LTA plus DMSO, the solvent for FASN-IN-3 (Compound 242A), results in secretion of IL-1 beta. FASN inhibitor 1 treatment of PBMC, which is a mixed population of mononuclear cells including both lymphocytes and monocytes, reduces the level of IL-1 beta resulting from either LPS or LTA stimulation. For monocytes, FASN-IN-3 treatment reduces the level of IL-1 beta resulting from LTA stimulation whereas there is only a slight reduction after LPS stimulation[1].
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