CH7057288
CAS No. : 2095616-82-1
| Size | Price | Stock |
|---|---|---|
| 5mg | $150 | In-stock |
| 10mg | $250 | In-stock |
| 25mg | $450 | In-stock |
| 50mg | $750 | In-stock |
| 100mg | $1350 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-107362 |
| M.Wt: | 569.67 |
| Formula: | C32H31N3O5S |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 34 mg/mL |
CH7057288 is a potent and selective TRK inhibitor. CH7057288 is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. IC50 & Target: TRK [1] In Vitro: CH7057288 induces regression of intracranial tumors and greatly improves event-free survival in an intracranial implantation model mimicking brain metastasis. CH7057288 can be a promising therapeutic agent for TRK fusion-positive cancer. TRK receptor tyrosine kinases are expressed as fusion proteins encoded by various fusion genes across a wide variety of cancer types, including lung and colorectal cancer[1].
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