PROTAC BET degrader-2
CAS No. : 2093388-33-9
| Size | Price | Stock |
|---|---|---|
| 5mg | $480 | In-stock |
| 10mg | $760 | In-stock |
| 50mg | $2300 | In-stock |
| 100mg | $3680 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-114228 |
| M.Wt: | 770.84 |
| Formula: | C41H42N10O6 |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic) |
PROTAC BET degrader-2 is a PROTAC connected by ligands for Cereblon and BET with an IC50 value of 9.6 nM in cell growth inhibition in the RS4;11 cells and capable of achieving tumor regression. IC50 & Target:IC50: 9.6 nM (BET in the RS4;11 leukemia cell line)[1]. In Vitro: PROTAC BET degrader-2 (compound 25) is a highly potent degrader of Bromodomain and Extra-Terminal (BET) proteins with an IC50 value of 9.6 nM in cell growth inhibition in the RS4;11 cells and capable of achieving tumor regression[1].
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