YM-60828 (methanesulfonate)
CAS No. : 209187-02-0
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| Cat. No. : | HY-10281 |
| M.Wt: | 633.74 |
| Formula: | C28H35N5O8S2 |
| Purity: | >98 % |
| Solubility: |
YM-60828 is an FXa inhibitor with antithrombotic properties. In the rat arteriovenous shunt model, YM-60828 does not prolong coagulation time but reduces the levels of thrombin-antithrombin III complex (TAT) in a dose-dependent manner. YM-60828 exhibits only anti-FXa activity and does not show anti-thrombin activity, indicating that its antithrombotic effect is independent of thrombin. Therefore, the antithrombotic effect of YM-60828 can be monitored by TAT[1].
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