PF-06745013
CAS No. : 2089334-01-8
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| Cat. No. : | HY-123965 |
| M.Wt: | 382.84 |
| Formula: | C21H19ClN2O3 |
| Purity: | >98 % |
| Solubility: |
PF-06745013 (Compound 37) is a MAP4K4 inhibitor without time-dependent inhibition (TDI) risk of CYP3A4 (IC50 of 0.4 nM for MAP4K4). PF-06745013 has no accumulation CNS-impaired and non-ATP competitive activities in mouse models. PF-06745013 can be used for inflammatory diseases like diabetes and cancers research[1].
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