NAcM-OPT


CAS No. : 2089293-61-6

2089293-61-6
Price and Availability of CAS No. : 2089293-61-6
Size Price Stock
5mg $35 In-stock
10mg $60 In-stock
25mg $120 In-stock
50mg $220 In-stock
100mg $350 In-stock
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Cat. No. : HY-111505
M.Wt: 434.40
Formula: C23H29Cl2N3O
Purity: >98 %
Solubility: DMSO : 125 mg/mL (ultrasonic)
Introduction of 2089293-61-6 :

NAcM-OPT is an orally bioavailable cullin neddylation 1 (DCN1) inhibitor, which potently inhibits the DCN1-UBE2M interaction[1]. IC50 & Target: DCN1[1] In Vitro: NAcM-OPT (Compound 67) is orally bioavailable, well tolerated in mice, and currently used to study the effects of acute pharmacologic inhibition of the DCN1-UBE2M interaction on the NEDD8/CUL pathway[1].

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