Propargyl-PEG3-alcohol


CAS No. : 208827-90-1

208827-90-1
Price and Availability of CAS No. : 208827-90-1
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100mg $6 In-stock
250mg $14 In-stock
1g $19 In-stock
5g $94 In-stock
25g $342 In-stock
100g $961 In-stock
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Cat. No. : HY-41921
M.Wt: 188.22
Formula: C9H16O4
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 208827-90-1 :

Propargyl-PEG3-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. Propargyl-PEG3-alcohol is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. In Vitro: PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

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